Occlusive Dressing/Drug Delivery Vehicle for PsoriasisThe goal of this project is to develop unique skin coating formulations for use as a combination occlusive dressing and drug delivery vehicle as a topical treatment for psoriasis. Psoriasis affects 1% to 3% of the world's population. Psoriasis is a chronic, disabling skin disease which is treated with multiple modalities, but for which there is no known cure. Hydrocolloid occlusive dressings, when applied independently or in conjunction with topical corticosteroids have been shown to improve outcomes. However, occlusive dressings are associated with local side effects and have limited patient acceptability because of poor cosmetic properties. The specific aims of the project are to optimize skin coating formulations for use as a sustained-release steroid treatment for psoriasis, to evaluate skin coating formulations with encapsulated steroids in vivo in an animal model, and to evaluate skin coating formulations with encapsulated steroids in vivo in a human clinical trial on psoriasis patients.
Biomedical
Development Corporation
500 Sandau,
Suite #200
San Antonio,
TX 78216
210.308.6196
fax
Email:
bdc@biodevcorp.com