One Step Antimicrobial Surgical Preparation and DrapeSurgical wound infections are an important cause of morbidity, mortality, and excess hospital costs. Surgical wound infections are the second most frequently found nosocomial infection overall and, among surgical patients, surgical wounds are the most common nosocomial infection site. The goal of this project is to develop unique coating formulations which can be used to replace the current 3-step scrub/disinfect/drape preoperative procedure with a one-step, sustained release, antimicrobial, preoperative skin preparation that also serves as a surgical incise drape. The coatings are applied in liquid form. In less than a minute, a tough, thin, dry, non-tacky, non-greasy, "breathable" film is created. The coating conforms to the contour of the skin and fits where placed without wrinkling, tearing, lifting, or bubbling. After application, it will remain intact for 8 hours or more but can easily be removed at anytime or will spontaneously flake away over about 24 hours. The specific aims of Phase I are to optimize the coating formulations, evaluate the microbicidal activity in vitro and in vivo, and test preliminary safety in animals.
Biomedical
Development Corporation
500 Sandau,
Suite #200
San Antonio,
TX 78216
210.308.6196
fax
Email:
bdc@biodevcorp.com