Frequently Asked Questions

1. What makes iCLEAN® Mouth Rinse better than other mouthwashes?

iCLEAN® offers a cleaning power that other over-the-counter mouthwashes can’t touch. Unlike other mouthwashes, iCLEAN® is powered by iodine (and not just any iodine!). Inside every bottle of iCLEAN®, our proprietary process is constantly generating powerful free iodine (I2) ions. The superior cleaning power of this innovative process means important benefits, like improving morning breath.

2. How does it work?

iCLEAN® stands for Iodine Cleans. With the iodine in iCLEAN®, nature’s chemistry is powering your mouthwash. Every time you swish, you’re getting fresh, active iodine (with a dash of flavoring) to keep your mouth healthy, while still tasting fresh and sweet. Nature’s swish keeps that slimy feeling off your teeth for a natural, beautiful smile. You might even feel like your teeth were freshly cleaned at the dentist.

Swish Before After

iClean has a "built in" timer! Before swishing, the iClean is a lovely pale amber color. After swishing (if you've swished effectively.. both with enough vigor and for enough time), the yellow color will disappear and your spittle will be clear or mostly clear (no yellow) when you spit the rest out. The act of swishing liberates the iodine from the liquid and the color shows how effectively you just swished. Try it yourself!

3. What is a “superior clinical result”?

Our affiliate, Biomedical Development Corporation (BDC), is a leading recipient of Small Business Innovative Research grants from the prestigious National Institutes of Health. BDC and leading scientists from respected universities work together to develop cutting edge technologies, including the unique free iodine technology that powers iCLEAN®.

At BDC, we focus on “superior clinical outcomes” which means that we get results that are scientifically proven to out-perform existing technologies.

Visit www.biodevcorp.com to learn more about the innovative technologies being developed at BDC.

4. Why is Iodine an important active ingredient?

Iodine is an essential nutrient for human life. It doesn’t get any more natural than that. For example, iodine is an essential component of your endocrine system and iodine is necessary for proper thyroid function. 

Using iCLEAN®’s unique iodine technology gives you a mouthwash that really works, while still staying true to Mother Nature.

To find out more about the benefits of iodine, click here.

5. What exactly is in iCLEAN®?

Only two ingredients: Iodine and flavoring. 

6.  Why does iCLEAN® contain flavorings?

Because some people don’t like the taste of pure iodine, we’ve added a small amount of non-sugar flavorings to give iCLEAN® a sweet, fresh taste.  (You’ll be pleasantly surprised to find that iCLEAN® does not have the harsh, minty taste of most mouthwashes.)

7. How much do I use?

Just 1 teaspoon (about a capful) once a day.

8. How often can I use it?

iCLEAN® Mouth Rinse is recommended for use once a day. 

9. How long will one bottle last?

One bottle will last approximately 45 days. 

(Try our easy Auto-ship option to “set it and forget it”.  You’ll have a new bottle at your door every 6 weeks without the hassle of re-ordering.) 

10.  Does iCLEAN® replace regular tooth-brushing?

iCLEAN® is designed to complement, not replace, your standard toothbrush. iCLEAN® reaches places your brush can’t. Use both and make your dentist proud!

11. How can having a cleaner mouth impact my overall health?

There are more bacteria in your mouth than there are people on the planet… and your mouth is the gateway into the body. In recent years, doctors have found links between oral health and debilitating illness such as diabetes, heart disease, eating disorders, and more. Oral health is absolutely related to whole-body health!
Here are some links to what the experts have to say:

Read more on our Total Health page!

12. If I have a medical condition related to iodine, can I use iCLEAN®?

Please consult your healthcare professional before using this product if you are pregnant or nursing, have a medical condition, are taking thyroid medication, are sensitive to iodine or are taking an iodine medication.

13. Will iCLEAN® stain my teeth?

When people think of iodine, they often imagine the dark brown povidone iodine used for wound cleaning. Our unique free iodine technology is completely different. iCLEAN® is a pale yellow color (some users call it ‘chardonnay’ or 'champagne' colored and in Kentucky folks claim it looks like ‘bourbon’). 


Tincture of iodine is also something completely different. While tincture of iodine stings because it contains alcohol (as does the typical minty mouthwash), iClean has a soothing, pleasant taste and feel on teeth and gums. iClean contains no alcohol; its only ingredients are iodine and a small amount of non-sugar flavoring.

While there is a small chance that iCLEAN® Mouth Rinse could leave a pale yellow stain on your teeth, in our clinical studies to date involving over 50 patients, no significant staining has ever been reported. Any slight discolorations were removed with a standard dental cleaning.

14. What do people say about iCLEAN®?

Check out our reviews on Amazon.

15. Can you ship outside the U.S. and if so, is there a shipping charge?

Currently, we offer international shipping to Canada, Mexico, and Europe.  Shipping charges vary and will be calculated at check-out by PayPal.  If you have any questions, please email us at info@iCLEANmouths.com

16. Where else can I buy iCLEAN® besides the iCLEAN® website?

Currently iCLEAN® is available online. Click here to order. You may also order on Amazon.com in the U.S. and Amazon.ca in Canada. 

To order by mail, please contact us at info@icleanmouths.com or call 210-374-1230.

We are in the process of establishing qualified distributors for iCLEAN®.  If you or someone you know is a licensed dentist or a healthcare practitioner and interested in qualifying as a distributor, please contact us.

17. How do I qualify to become a distributor of iCLEAN®?

If you are interested in becoming an iCLEAN® distributor, please contact us at info@iCLEANmouths.com.

18. History of Iodine

Iodine was discovered in 1811 by Bernard Courtois, a French chemist. He was searching for a way to help restore the diminishing supply of gunpowder for Napoleon's army.  When he turned to seaweed as a source of potassium carbonate for the manufacture, he inadvertently produced a purple vapor cloud. He found that he could condense the vapor into a violet-black substance which he named "Substance X".  He suspected that he had found a new element but funds were scarce due to the war effort.

The substance later was evaluated by multiple chemists in different countries to the point there later became controversy over who had found this new element. Along the way, it was named iodine after the Greek word ioeides, which means "violet colored".

Since those raw beginnings, iodine has enjoyed an important role in medicine as both an antiseptic and for the prevention of disorders caused by iodine deficiency, such as goiter and hypothyroidism.  

Iodine is a natural element and essential to life.

Learn more about iodine:


Learn more about the history of iodine:


19. Where can I find out more about iCLEAN®?

Have a question we haven’t answered here?  Please feel free to email us anytime at info@iCLEANmouths.com and we will respond promptly.

An Important Note about “Iodine Allergy”:

One common misconception associated with the use of iodine is that it induces sensitization. However, allergic reactions to iodinated products are caused by ingredients that exist in conjunction with iodine, and not by the iodine itself. For example, reactions to iodinated contrast media occur in 0.5 to 2% of recipients,(1) but the reaction is due to nonspecific immune mediators against the contrast medium, and not the iodine.(2) Adverse reactions to povidone-iodine, although uncommon, are classified as skin irritation reactions that involve the povidone component and do not involve the iodine component.(2) Allergies to seafood are due to IgE-mediated hypersensitivity reactions to seafood proteins and not to iodine in the food. Thus, there is no cross-reactivity between these three sources of iodine, indicating that iodine allergy is either very rare, does not exist, or that methodology used in studies examining iodine allergy was flawed.(2) A Position Statement by the American Academy of Allergy, Asthma and Immunology on the use of potassium iodide for radiation emergencies affirms the latter statement.(3-5)

1. Webb JA, F Stacul, HS Thomsen, and SK Morcos, Late adverse reactions to intravascular iodinated contrast media. Eur Radiol, 2003. 13(1): p. 181-4.
2. Coakley FV and DM Panicek, Iodine allergy: an oyster without a pearl? AJR Am J Roentgenol, 1997. 169(4): p. 951-2.
3. American Academy of Allergy Asthma and Immunology, Academy Position Statement: The Risk of Severe Allergic Reactions from the Use of Potassium Iodide for Radiation Emergencies. February 24, 2004.
4. Hill J and LM Hill, Allergic to PVP? A discussion of alternatives. Insight, 2004. 29(3): p. 22-6; quiz 27-8.
5. Sampson HA, 9. Food allergy. J Allergy Clin Immunol, 2003. 111(2 Suppl): p. S540-7.